Diagnostic challenges refer to the difficulties, complexities, and obstacles that healthcare professionals encounter when trying to accurately identify and diagnose a medical condition or illness in a patient. These challenges can arise from a variety of factors, such as the complexity of the disease itself, overlapping symptoms with other conditions, limitations of available diagnostic tests, variability in patient presentation, and lack of clinical experience or expertise. Improving diagnostic accuracy and efficiency is crucial for providing patients with timely and appropriate treatment. Addressing diagnostic challenges often involves utilizing advanced diagnostic technologies, interdisciplinary collaboration among healthcare providers, continuous medical education and training, and paying attention to patient’s medical history and symptoms. By overcoming these challenges, healthcare professionals can improve patient outcomes, reduce misdiagnoses and unnecessary treatments, and ultimately enhance the overall quality of care provided to patients.